Taiwan

Host genetics-driven expansion of invasive Escherichia coli in the gut microbiome exacerbated tumorigenesis by targeting Hippo pathways to induce cancer stemness via CD44 upregulation. Mouse models of Apc gene mutation and bacteria-epithelial cell cocultures provided proof of concept that invasive bacteria derived from commensal microbes enhanced epithelial clonogenicity. Our data support the use of bacterial precision medicine as an alternative strategy for managing colorectal cancers, even in the hereditary subset.

Layered carbide-carbon hybrids offer scalable, high-rate SLFB electrode platforms for improved wettability and enhanced electrolyte-electrode interaction and redox kinetics.

Researchers developed a highly filled liquid epoxy for chip packaging that remains easy to process despite its exceptionally high silica content. By optimizing particle packing, surface treatment, and rubber nanoparticle reinforcement, the material minimizes wafer warpage while maintaining excellent toughness and reliability during packaging.

This work reveals how lithium migrates in solid-state batteries and shows that fast charging can cause irreversible lithium migration.

Researchers have developed a robotic platform that identifies Gram-positive and Gram-negative bacteria through touch-based electrical signals, without staining or chemical labels. Selected as a cover article in Nano Energy, the study achieved rapid classification within 0.62 seconds and 90.93% accuracy.

Researchers at National Taiwan University and the University of Southern Denmark show that obesity in male mice raises let-7 microRNAs in sperm, which silence the enzyme DICER1 and impair mitochondrial function in the fat tissue of their offspring. Weight loss reverses part of the effect in both mice and men.

Researchers developed a hybrid supercapacitor electrode by anchoring two-dimensional vanadium disulfide nanosheets onto one-dimensional porous graphitic carbon nitride nanotubes. The mixed-dimensional structure improves ion transport, charge storage, and cycling stability, offering a promising strategy for fast and durable energy storage.

Research led by National Yang Ming Chiao Tung University and National Taiwan University uncovers a successful postnatal gene therapy strategy that restores hearing and preserves inner ear structures in a hereditary deafness model. This breakthrough identifies vital therapeutic windows after birth, paving a clear path toward clinical translation for genetic hearing loss.

A research team from National Taiwan University and University of Oslo analyzed data on more than 1.3 million children across two countries, finding that an earlier European safety signal weakens to non-significance once underlying disease and other confounders are accounted for.

A groundbreaking study reveals how fine particulate matter (PM2.5) fuels bladder cancer malignancy by triggering Epithelial-Mesenchymal Transition (EMT) via the ERK/WNT/beta-catenin pathways. These findings provide critical evidence of air pollution's destructive molecular reach far beyond the respiratory system, promoting tumor metastasis.

Each unit of cost invested in Helicobacter pylori screening can generate approximately a five-fold return in gastric cancer prevention benefits.

Researchers in Taiwan have developed a cell-free extracellular matrix material from axolotl skin that helped mouse burn wounds close faster and showed signs of reduced fibrotic scarring. The findings suggest that one of nature’s most remarkable regenerators may inspire future strategies for burns, chronic wounds, and surgical injuries, but the approach is not yet a treatment for human wounds.

Researchers have developed an AI system that automatically figures out where an inspection photo was taken inside a building by matching it to the building's digital model, with no GPS or manual tagging required. The system achieved under two meters of location error and dramatically outperformed existing AI approaches.

Researchers from National Taiwan University (NTU) and National Taiwan University Hospital (NTUH) have identified a promising way to reinvigorate the body's cancer-fighting immune cells by rewiring their metabolism, revealing a potential new strategy for cancer immunotherapy.

Researchers at National Taiwan University refined a pseudo-germ-free mouse model to make gut microbiome studies safer for mice and more reliable. Using this model, they found that antibiotic-driven changes in gut microbes suppressed pancreatic tumor growth and enhanced the effect of gemcitabine chemotherapy.

By engineering a bismuth thin film / twisted bilayer MoS2 heterostructure, the research work achieved precise bidirectional electron confinement without any applied voltage. Moiré potential controls horizontal electron localization; Bi film thickness tunes vertical effective mass - switching electron configurations between a trimer and a Kagome-like arrangement. The voltage-free confinement mechanism offers a material foundation for charge qubits and ultra-low-power semiconductors.

A new study from Taiwan combines consumer behavior research and life cycle assessment to design reusable cup systems that people are more willing to use. The findings show that convenience and incentives strongly shape participation, while well-designed reusable cup systems can still reduce environmental impacts compared to single-use cups.

Scientists from National Taiwan University and St. Paul’s Hospital have demonstrated how AI can leverage routine chest X-rays to detect asymptomatic bone loss, closing critical gaps in screening healthy Asian populations.

By quantitatively analyzing 100 soil samples collected across Fukushima Prefecture in 2011, researchers found that cesium-rich microparticles (CsMPs) were distributed over a wide area, with abundances ranging from 0 to 52.3 particles g⁻¹ and accounting for up to 61.9% of the total radioactivity in some samples. Their results further revealed that most CsMPs originated from a single radioactive plume released on 15 March 2011, whereas later emissions contained mainly water-soluble cesium rather than particulate CsMPs.

By regulating EGFR trafficking to late endosomes and attenuating AKT and ERK signaling, CASK suppresses p21 expression and promotes proliferation in NSCLC cells.

The study from National Taiwan University reveals a single-layer zigzag-type metallic glass film with precisely tunable emissivity for thermal infrared camouflage technology.

Researchers from National Taiwan University develop advanced expansion microscopy methods that enable nanoscale visualization of centriole architecture using conventional fluorescence microscopes and superresolution imaging.

National Taiwan University Hospital (NTUH), in collaboration with multiple medical centers across Taiwan, has found that patients with hepatitis C remain at a significantly elevated risk of hepatocellular carcinoma (HCC) even after successful viral eradication with direct-acting antivirals (DAAs), particularly if metabolic dysfunction–associated steatotic liver disease (MASLD) is present.

By combining demand-driven life cycle assessment with a multi-objective optimisation framework, researchers identified potential optimal solutions for reusable bubble tea packaging systems under actual market demand conditions. The results show that material selection and low reuse frequency dominate both economic costs and environmental impacts, while durability and logistics become increasingly important as reuse frequency increases.

Researchers at National Taiwan University and partner institutions, led by research associate Dr. Raúl Tapia and Associate Professor Sze Ling Ho at the Institute of Oceanography, have uncovered new evidence that Antarctic Intermediate Water (AAIW) — a distinct layer sitting 500–1,500 meters below the ocean surface — played a pivotal role in a major atmospheric carbon dioxide transition that occurred roughly 450,000 years ago. The findings, published in Science Advances, challenge the prevailing view that changes in the deepest layers of the Southern Ocean alone drove this shift, and point instead to intermediate-depth circulation as a previously underestimated regulator of Earth’s carbon cycle.

Researchers have developed a new framework that uses artificial intelligence to monitor wastewater treatment in real time, ensuring environmental safety while maximizing resource recovery. This “twin transition” approach allows facilities to predict system health and optimize energy use simultaneously.

Researchers at National Taiwan University developed bioinspired composites that mimic bone and bamboo structures to improve strength and toughness simultaneously. Using artificial intelligence, simulations, and 3D printing, the team discovered how soft layers near cracks can prevent catastrophic failure.

Researchers at National Taiwan University have developed a liver-directed IL-10 gene therapy that strengthens cancer-fighting immune cells and suppresses liver tumors in mice. The treatment also generated long-lasting immune memory cells that remained in the liver after tumors disappeared.

Dynamic catalyst interfaces offer a smarter route for converting CO2 into formic acid.

Data-driven models provide precise prediction on charging-phase of desalination technology building a bridge between data-driven insights and physicochemical principle to lay a strong foundation for system parameter optimization.